Clinical Trials Information
For more detailed information on available clinical trials, and the clinical trial process please view this section on the Parkinson Society Canada website. Parkinson Society Central & Northern Ontario (CNO) does not have the resources to screen or evaluate the background, ethics or intent involved in this research proposal. CNO neither encourages nor discourages involvement in this project; however, we want to be sure that people with Parkinson's have the information they need to make an informed decision. Therefore, we share this information with the understanding that CNO assumes no liability for providing access to information and—if you are interested—encourages you to review the request and ensure that it will work for you, in consultation with your health care team, before proceeding to contact the research group. Investigational medication in Idiopathic Parkinson’s Disease (IPD) With Motor Fluctuations, as Add-on to Levodopa (SETTLE). The investigational medication is an inhibitor of MAO-B (Monoamine-Oxidase-B). MAO-B compounds enhance the effect of dopamine by preventing its breakdown. The investigational medication is being studied as a phase III trial to evaluate its effectiveness and safety as add-on therapy to a stable dose of levodopa. The study will measure the increased daily "on" time for a person with Parkinson’s during an 18-hour diary-recording period. The study is looking for men and women between the ages of 30 to 80 years with a confirmed diagnosis of Parkinson’s of more than 5 years. Participants should also be receiving treatment for their Parkinson’s symptoms with a stable dose of levodopa for at least 4 weeks. Sites in CNO:
Brain Imaging Research for understanding Parkinson's seeking participants. Centre for Addiction and Mental Health is looking for participants for brain imaging research for understanding Parkinson's. This study involves MRI and PET. Recruiting both patients with Parkinson's and age-matched healthy volunteers within the age group of 55-75. For further information, please contact Dr. Ji Hyun Ko via jihyun.ko@camhpet.ca or 416-535-8501x7396. |
